How medical laboratories fit within the broader healthcare delivery structures. How does the healthcare system work in India? The topics are discussed in detail in the slides.
Analyzing change in metabolic homeostasis and cytokine signalling during immune-tumour cell interactions and generation of anti-tumour immune response using adjuvant coated therapy along with limiting the immune regressive signals Introduction Tumor cells evade immune response by taking advantage of peripheral tolerance. Peripheral tolerance is the downregulation of T-cell priming and getting rid of auto-reactive T-cells at the lymphatic system and tissue site. T-cell priming is the activation of T-cells in response to foreign antigens and to generate an immune response against it. In this process, the T-cell receptor (TCR) binds to the antigen displayed in MHC on the surface of antigen-presenting cells. Sufficient binding of co-stimulatory molecules such as CD80 and CD86 (B7 family) present on APC binds to CD28 on T-cells to upregulate proliferation and increase survival of T-cells (10). Immune checkpoints such as CTLA-4 and PD-1 help...
Constructing synthetic complex life system acclimatised to the Martian soil: Analysing complex system behaviour on the Red Planet Objectives: Create an autonomous system on Mars using a combination of mitochondria, cyanobacteria, and water-producing bacteria. Acclimatising the system as per Martian gravity and atmosphere will leverage photosynthesis, respiration, and water production to maintain homeostasis and propagate on Martian soil. Atmosphere of Mars: Carbon dioxide (CO2): 95% by volume at the surface Molecular nitrogen (N2): 2.6% Argon (Ar): 1.9% Molecular oxygen (O2): 0.16% Carbon monoxide (CO): 0.06% Luckily, CO2 can be used as a source of energy to create low-carbon fuels and release O2 as a byproduct. However, increased O2 levels need to be utilised, such as in OxPhos if we are working in a complex system, or an extra O2 byproduct can be released to make the atmosphere more oxygenic if done in maximum affordable scalability. Introduction:...
In any scientific field, especially in medical laboratory technology, biotechnology, and life sciences , working in the lab responsibly and systematically is just as important as the experiments themselves. This is where Good Laboratory Practices (GLP) come in. GLP provides a set of principles designed to ensure: Accuracy and reliability of experimental data. The safety of laboratory workers is ensured by following correct procedures. Proper handling of equipment, reagents, and samples. Compliance with regulatory standards in research and diagnostics. I have uploaded a PowerPoint presentation on Good Laboratory Practice to help students quickly understand the basics of GLP in a structured, easy-to-learn format.
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