How medical laboratories fit within the broader healthcare delivery structures. How does the healthcare system work in India? The topics are discussed in detail in the slides.
Introduction The cellular import and export pump aid in the maintenance of calcium signaling homeostasis by altering cytosolic Ca+2 concentration, which may be reversed by pumps. Calcium is imported into the cell by voltage-dependent calcium channels (VDCC), SOCC, NSCC, NCX (exchange), and NCKX (co-transport) from the extracellular side. It may also be exported out of the ER and SR via RyR controlled by IP3R to regulate the cytosolic concentration of calcium (100nM-1mM). SERCA pumps restore calcium ions into the ER and SR after voltage-gated Ca+2 channels export calcium ions out of the cell. CaN activation (PP2B), followed by NFAT dephosphorylation. Cyclosporin and voclosporin are two medicines that target CaN. Calcium Sensors and Adaptors Calmodulin (CaM) - Ubiquitous adaptor protein and specifically bind to Ca+2. ❖ Contain EF Hand domain (helix-loop-helix motif) bind to Ca. ❖ Ca bind to 7 O2 atoms (chelate Ca+2) of aa in a bipyramidal pentagonal shape. ❖ Binding with Ca induces dimer...
In any scientific field, especially in medical laboratory technology, biotechnology, and life sciences , working in the lab responsibly and systematically is just as important as the experiments themselves. This is where Good Laboratory Practices (GLP) come in. GLP provides a set of principles designed to ensure: Accuracy and reliability of experimental data. The safety of laboratory workers is ensured by following correct procedures. Proper handling of equipment, reagents, and samples. Compliance with regulatory standards in research and diagnostics. I have uploaded a PowerPoint presentation on Good Laboratory Practice to help students quickly understand the basics of GLP in a structured, easy-to-learn format.
While no single meal will kill cancer, a balanced and nutritious diet may substantially lower your risk. Here are some ideas on what meals to include and which to restrict or avoid by not only cancer patients or the general population who might be at higher risk. Foods to include Fruits and vegetables are rich in vitamins, minerals, and antioxidants that help protect against various types of cancer. Whole grains: Foods like brown rice, quinoa, oats, and whole wheat contain fibre and other nutrients that are beneficial for overall health. Lentils and Pulses: Eating high-fibre foods reduces the risk of bowel cancer. Lean proteins: Include sources like fish, poultry, beans, and tofu. Limit processed meats like bacon, sausage, and deli meats, which have been linked to an increased risk of cancer. Healthy fats: Choose sources like nuts, seeds, avocados, and olive oil. These fats have anti-inflammatory properties and can promote overall health. Herbs and spices: Many herbs and spi...
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