Molecular Science

How medical laboratories fit within the broader healthcare delivery structures. How does the healthcare system work in India? The topics are discussed in detail in the slides. 

In any scientific field, especially in medical laboratory technology, biotechnology, and life sciences , working in the lab responsibly and systematically is just as important as the experiments themselves. This is where Good Laboratory Practices (GLP) come in. GLP provides a set of principles designed to ensure: Accuracy and reliability of experimental data. The safety of laboratory workers  is ensured by following correct procedures. Proper handling of equipment, reagents, and samples. Compliance with regulatory standards in research and diagnostics.  I have uploaded a PowerPoint presentation on Good Laboratory Practice to help students quickly understand the basics of GLP in a structured, easy-to-learn format. 

Analyzing change in metabolic homeostasis and cytokine signalling during immune-tumour cell interactions and generation of anti-tumour immune response using adjuvant coated therapy along with limiting the immune regressive signals Introduction       Tumor cells evade immune response by taking advantage of peripheral tolerance. Peripheral tolerance is the downregulation of T-cell priming and getting rid of auto-reactive T-cells at the lymphatic system and tissue site. T-cell priming is the activation of T-cells in response to foreign antigens and to generate an immune response against it. In this process, the T-cell receptor (TCR) binds to the antigen displayed in MHC on the surface of antigen-presenting cells. Sufficient binding of co-stimulatory molecules such as CD80 and CD86 (B7 family) present on APC binds to CD28 on T-cells to upregulate proliferation and increase survival of T-cells (10).       Immune checkpoints such as CTLA-4 and PD-1 help...